Most Commonly Used Medications to Control Lupus Disease

Lupus Disease
Lupus Treatment Guide

Treatment for lupus disease depends on the symptoms and signs. Finding out whether both have to be treated and which drugs to use require a careful consideration of the risks these have and the benefits these offer.

Non-steroidal Anti-Inflammatory Drugs

NSAIDs may be bought without prescription and used to treat not just pain and swelling, but also fever related to lupus. Much stronger medications can be bought through prescription. Some side effects of these drugs are stomach bleeding, kidney issues and an increased likelihood of heart problems.


Corticosteroids such as prednisone and others can counter the lupus inflammation. High doses of methylprednisolone are usually used to control severe disease, involving the brain and kidneys. Some of the side effects are easy bruising, weight gain, thinning bones, high blood pressure (BP), diabetes, more risk of infection, etc. You are likelier to have side effects if you take higher doses and undergo longer term therapy.

Anti-malarial Drugs

Commonly used medications to treat malaria have an effect on the immune system, plus these can help reduce the possibility of lupus flares. Some of the side effects are stomach upset, and seldom damage to your retina. Regular eye examinations are recommended when you take these drugs.


Medications that suppress your immune system may help treat severe cases of lupus. Some examples are azathioprine, methotrexate and mycophenolate mofetil. Potential side effects include an increased possibility of infection and cancer, reduced fertility, and liver damage.


An intravenous infusion of another kind of medication called belimumab into the body also alleviates the symptoms of lupus in some individuals. Side effects include infections, diarrhea and nausea. Aggravation of depression can also rarely occur.

Alternative Treatment

Those with lupus sometimes seek complementary or alternative medicine. While no alternative therapies have been proven to change the course of this condition, some may help alleviate its symptoms.

Talk about these treatment options with your medic before you initiate these on your own. Your doctor can help measure the risks and benefits, and inform you whether the following will interfere with your existing drugs.

DHEA Supplements

Supplements that contain DHEA may help reduce both fatigue and muscle pain. DHEA might cause acne in ladies.

Fish Oil Supplements

These supplements have omega-3 fatty acids, which may be useful for those who have lupus. Possible side effects of these are belching, nausea etc.